Overview

The Effect of Pnemoperitoneum on Intracranial Pressure and Cerebral Oxygenation During Laparoscopic Surgery According to Anesthesia Agents: Propofol Based Total Intravenous Anesthesia vs Desflurane Anesthesia

Status:
Withdrawn

Trial end date:
2015-10-01

Target enrollment:
0

Participant gender:
All

Summary

The pneumoperitoneum during laparoscopic surgery have the potential to cause an increase of intracranial pressure (ICP). Previous studies have proposed that ultrasonographic measurements of the optic nerve sheath diameter (ONSD) correlate with signs of increased ICP. The aim of this study is to compare the effect of pnemoperitoneum on intracranial pressure and cerebral oxygenation during laparoscopic surgery according to anesthesia agents, propofol based total intravenous anesthesia (TIVA group) and desflurane anesthesia (Des group).

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Yonsei University

Treatments:

Anesthetics
Desflurane
Isoflurane
Propofol

Criteria

Inclusion Criteria:

- Adult patients (20-80 years of age) scheduled for laparoscopic cholecystectomy
undergoing general anesthesia

Exclusion Criteria:

- Patients with previous history of neurologic disease, carotid disease, transient
ischemic attack, ocular disease and ocular surgery