The Effect of Povidone-iodine Ophthalmic Surgical Prep Solution on Respiration in Children Undergoing Strabismus Surgery With General Anesthesia.

• Status: Completed
• Trial end date: 2018-09-19
• Target enrollment: 0
• Participant gender: All

Summary

Determine whether the application of povidone-iodine ophthalmic solution onto the ocular surface causes a change in respiration in children undergoing strabismus surgery with general anesthesia.

Hypothesis: The application of povidone-iodine ophthalmic solution to the ocular surface causes a change in respiration in children during general anesthesia prior to strabismus surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Medical University of South Carolina
• Treatments: Anesthetics; Cadexomer iodine; Iodine; Ophthalmic Solutions; Pharmaceutical Solutions; Povidone; Povidone-Iodine

Criteria

• Inclusion Criteria

• Children between the ages of 1 year and 17 years

• Scheduled for strabismus surgery

• Anesthesia plan includes inhalational induction with sevoflurane and the use of a laryngeal mask airway (LMA) with spontaneous ventilation, per the attending anesthesiologist.

Exclusion Criteria

• History of an adverse reaction to iodine

• History of any thyroid disease

• Patients who require tracheal intubation, as determined by the attending anesthesiologist; e.g. craniofacial anomalies.

• Patients with a contraindication to sevoflurane, such as malignant hyperthermia or severe left ventricular dysfunction.

• Inability or unwillingness of the subject or legal guardian/ representative to give informed consent.