Overview

The Effect of Prophylactic Antibiotics on Surgical Site Infection Lower Limb Skin Excisions

Status:
Active, not recruiting
Trial end date:
2023-09-01
Target enrollment:
Participant gender:
Summary
The incidence of surgical site infection (SSI) infection in clean dermatologic surgery is very low, between 1-3%. Studies have demonstrated a much higher infection rate in skin excision surgeries in the lower limbs, up to 10% in most studies, and even 35.7% infection rate in a recent study from Australia. To our knowledge, there are no clinical trials demonstrating the efficacy of prophylactic antibiotic given prior to skin lesion excision from the lower limbs.
Phase:
N/A
Details
Lead Sponsor:
Rambam Health Care Campus
Treatments:
Anti-Bacterial Agents
Antibiotics, Antitubercular
Cephalexin
Clindamycin
Clindamycin palmitate
Clindamycin phosphate