The Effect of Prophylactic TPO Combined with BMS-IMRT to Esophageal Cancer Patients
Status:
COMPLETED
Trial end date:
2024-12-31
Target enrollment:
Participant gender:
Summary
The goal of this interventional study is to explore the protective effect of prophylactic TPO combined with bone marrow sparing (BMS)-IMRT in patients with esophageal cancer undergoing concurrent chemoradiotherapy. The main purpose is to reduce the incidence of all grades of thrombocytopenia from 35% to less than 10% by the intervention of study.
Participants will initiate concurrent chemoradiotherapy within 2 weeks after enrollment,and they will receive subcutaneous injection of recombinant human thrombopoietin (rhTPO) 15000U once a week during the radiotherapy.
Phase:
PHASE2
Details
Lead Sponsor:
JIANYANG WANG
Collaborator:
Cancer Institute and Hospital, Chinese Academy of Medical Sciences