The Effect of Protease Inhibitors on the Pharmacokinetics of Oral Norethindrone Contraception
Status:
Completed
Trial end date:
2014-09-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to learn if women taking the atazanavir and ritonavir have lower
levels of a birth control medication called norethindrone. Norethindrone (also called the
mini pill) is an FDA (Food and Drug Administration) approved progestin-only birth control
pill used to prevent pregnancy. Norethindrone is the standard medication used in women who
take the progestin only pill to prevent pregnancy. There are other birth control pills which
contain different medications. The investigators want to learn if HIV medications (atazanavir
and ritonavir) make the blood level of this birth control pill higher or lower. If the levels
of norethindrone are too low it may not work to prevent pregnancy. The investigators also
hope to learn about changes in the vaginal fluids and cervical fluids when women are taking
this birth control pill.