The Effect of Renin Angiotensin System Blockage (RAS) Blockade On PTX3 Levels In Diabetic Patients With Proteinuria
Status:
Completed
Trial end date:
2008-03-01
Target enrollment:
Participant gender:
Summary
Long pentraxin 3 (PTX3) is a recently discovered multimeric inflammatory mediator
structurally linked to CRP and serum amyloid P-component. There is no data about the effects
of Renin angiotensin system blockage (RAS) on PTX3 levels in diabetic patients with
proteinuria. The aim of this study was to find out whether the beneficial effects of RAS
blockage in diabetic proteinuria has any relation with the alteration of PTX3 levels. We
searched for the effects of ACE inhibitor ramipril on the clinical and laboratory parameters
of diabetic patients with proteinuria.