The Effect of Retrobulbar Block for Eye Surgery on Brain Oxygenation and Cognitive Functions in Elderly Patients

• Status: Completed
• Trial end date: 2016-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators measured changes in cerebral oxygen saturation (rSO2) and MMSE scores after retrobulbar block performed with levobupivacaine and lidocaine in patients undergoing vitreoretinal surgery.A total of 66 patients over the age of 60 undergoing vitreoretinal surgery with a total duration of less than 1 hour were included in this prospective, double-blinded study. The patients were randomly divided into two groups: group L (5ml, 2% lidocaine) and group LB (5ml, 0.5% levobupivacaine). Bilateral rSO2 measurements were recorded before the retrobulbar block and at 1-5 minutes post-block, during the procedure, and at 10-40 minutes post-op. MMSE was performed preoperatively and postoperatively in order to evaluate short term cognitive function. Sensory and motor block durations, pain, akinesia and conjunctival feeling scores, patient-surgeon satisfaction, and complications were also recorded.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cengiz KAYA
• Collaborator: Ondokuz Mayıs University
• Treatments: Bupivacaine; Levobupivacaine; Lidocaine

Criteria

Inclusion Criteria:

• Undergoing vitreoretinal surgery (total duration < 60 minutes)

• The ASA (American Society of Anesthesiologists) Classification I-III

• Over the age of 60

• The patiens who had no cognitive dysfunction

Exclusion Criteria:

• Contraindication for retrobulbar block

• Preoperative systolic blood pressure of 180 mmHg, diastolic blood pressure of above 100 mmHg

• Uncontrolled diabetes

• Body mass index ≥ 30 kg/m2

• MMSE ≤ 24

• Advanced organ failure

• Hb < 9gr/dl