The Effect of Riboflavin on Moderate to Severe Plaque Type Psoriasis
Status:
Active, not recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the anti-inflammatory effect of high-dose
riboflavin supplementation on chronic plaque psoriasis. Psoriasis is a common chronic skin
disorder that affects over 4 million people. There is no cure for psoriasis and treatment is
directed at controlling patients' symptoms. Amongst patients with skin disease, there is
significant interest in using complementary alternative medicine and vitamins to treat their
disease. Previous human case reports suggest that riboflavin, commonly known as Vitamin B2,
is clinically effective for the treatment of psoriasis; however, they were not conclusive.
More recent human trials have shown that 400 mg of daily oral riboflavin is a safe and
well-tolerated medication to administer to humans. For the purpose of this study, the
riboflavin is used as an investigational drug.