The Effect of S-ketamine for Patients Undergoing Electroconvulsive Therapy (ECT)

• Status: Not yet recruiting
• Trial end date: 2021-01-31
• Target enrollment: 0
• Participant gender: All

Summary

This study will determine the effectiveness and safety of S-Ketamine in depression patients undergoing electroconvulsive therapy.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yan Qiu
• Treatments: Esketamine; Ketamine

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists (ASA) Physical Status I-II

• diagnose depressive disorders with DSM-IV

• Without cognitive impairment

• Without ECT in past 6 months

Exclusion Criteria:

• had other comorbid psychiatric diagnoses, including schizophrenia, mania

• organic heart diseases, severe hypertension and arrhythmia

• severe hepatic and renal diseases

• severe cerebrovascular disorder or malformation, intracranial mass lesions and seizure

• glaucoma or high intraocular pressure and intra-ocular pathology

• severe haematological disease, fracture and obesity, pregnancy

• severe respiratory tract disease or difficult ventilation or incubation

• had pre-existing neurological disease or cognitive impairment

• allergy to anesthetics

• drugs abuse or alcohol addiction

• family history of malignant hyperthemia

• refuse to participate in this trial, had taken part in other clinical trial and with less education and couldn't understand the content of questionnaire