The Effect of Sevoflurane and Desflurane on Clara Cell Protein on the Lung

• Status: Enrolling by invitation
• Trial end date: 2021-06-20
• Target enrollment: 0
• Participant gender: All

Summary

Inhalation anesthesia; It means that the anesthetic drugs taken by the respiratory tract pass into the blood through the lung alveoli, reach the brain tissue, and create an anesthetic effect according to the density in the brain tissue. All inhalation anesthetics affect organ functions to varying degrees. Clara cell has been shown to have cell regeneration, immunomodulatory, anti-inflammatory and antioxidant activity in the bronchial epithelium. It is also thought that some substances accumulated in the respiratory system participate in the detoxification. Clara cell protein acts as a protein marker that indicates the severity of airway injuries after exposure to irritants. In this study, we planned to investigate the effect of inhalation anesthetics on Clara cell protein in liver transplant donors who will undergo hepatectomy surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Inonu University
• Treatments: Desflurane; Propofol; Sevoflurane

Criteria

Inclusion Criteria:

• living liver donors

Exclusion Criteria:

• smoking

• under 18 years

• over 65 years

• Patients who refused written informed consent forms