The Effect of Sildenafil and Tadalafil on Skeletal Muscle and Perceptual Fatigue
Status:
Completed
Trial end date:
2015-06-01
Target enrollment:
Participant gender:
Summary
This study is funded by the Moody Endowment. In this project, we will investigate the
potential effect of skeletal muscle nitric oxide (NO) production on skeletal muscle
anabolism, muscle strength, physical function, and body composition in older individuals.
Further, we will determine whether augmentation of NO-mediated signaling reduces fatigue and
fatigability.