The Effect of Smoking on Thermoregulation

• Status: Completed
• Trial end date: 2014-05-01
• Target enrollment: 0
• Participant gender: Male

Summary

To the best of our knowledge, a possible relation between smoking and heat injuries or heat intolerance was never scientifically examined, although such a relation is logical according to the observations that smoking has a thermogenic effect, decreases physical fitness and affects the body's heat dissipation.16 healthy young male volunteers will participate in the study, 8 smokers and 8 non-smokers. They will arrive to our lab four or six times. They will perform VO2 test and heat tolerance test (HTT) in different conditions.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Sheba Medical Center
• Collaborator: International Diabetes Federation
• Treatments: Nicotine

Criteria

Inclusion Criteria:

• age 18-30

• healthy

• after medical checkup

• after signing concent form

• for the smokers: smoking 0.5-1.5 packs of cigarettes a day at least 2 years.

Exclusion Criteria:

• heart disease

• respiratory disease

• baseline bp above 140/90 mmHg

• diabetes

• anhydrosis

• skin disease

• acute illness

• detoxification from nicotine

• allergy to nicotine

• smoking other then specified in the inclusion criteria