The Effect of Sodium Bicarbonate on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery

• Status: Completed
• Trial end date: 2016-08-23
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of study is to test whether perioperative sodium bicarbonate infusion can prevent acute kidney injury following open heart surgery in infective endocarditis patients.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yonsei University

Criteria

Inclusion Criteria:

• adult patients over the age of 20 scheduled for open heart surgery for infective endocarditis

Exclusion Criteria:

• end stage renal disease (serum creatinine concentration > 300 μmol/L)

• on dialysis

• chronic moderate to high dose corticosteroid therapy (> 10 mg/day prednisolon or equivalent)

• preoperative severe hypernatremia (Na+ > 150 mmol/L), alkalemia (PH > 7.50), or pulmonary edema

• neurocognitive dysfunction