The Effect of Sucralfate Slurry in Patients With Eosinophilic Esophagitis

• Status: Completed
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Could Sucralfate be a non-steriodal treatment option for patients with Eosinophilic esophagitis?

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mayo Clinic
• Treatments: Sucralfate

Criteria

Inclusion criteria:

• Patients between the ages of 18 and 80 with eosinophilic esophagitis diagnosed by a combination of compatible symptoms, endoscopic findings, histology, and lack of response to proton pump inhibitors.

Exclusion criteria:

• Medical conditions such as severe heart or lung disease that preclude safe performance of endoscopy

• Pregnant and lactating females will be excluded

• Diabetic patients will be excluded as episodes of hyperglycemia have been reported

• Patient with chronic renal failure/on dialysis will be excluded

• Patients with conditions known to be associated with esophageal eosinophilia, including Crohn's disease, Churg-Strauss, achalasia, and hypereosinophilic syndrome

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