The Effect of Tight Glycemic Control on Surgical Site Infection Rates in Patients Undergoing Open Heart Surgery

• Status: Completed
• Trial end date: 2011-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study was to investigate the effects of three different glycemic treatment conditions (tight, conventional, and standard) in the intraoperative period on: 1) postoperative surgical site infections, and 2) postoperative procalcitonin, and C-reactive protein levels in patients undergoing open-heart surgery. Secondary aims of the study were to investigate the effects of the three glycemic treatment conditions on: 1) intraoperative blood glucose; 2) intraoperative glycemic stability; and 3) intensive care unit length of stay, in patients undergoing open-heart surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: James A. Haley Veterans Administration Hospital
• Collaborators: American Association of Nurse Anesthetists; University of South Florida
• Treatments: Insulin; Insulin, Globin Zinc

Criteria

Inclusion Criteria:

• over the age of 21

• on cardiopulmonary bypass or off cardiopulmonary

• elective or urgent coronary artery bypass graft (CABG) surgery

• CABG with or without combined valve surgery

• valve surgery

Exclusion Criteria:

• chronically immunosuppressed

• suffered from end-stage organ disease

• currently had active infections

• underwent emergent or salvage CABG surgery

• had an implanted insulin pump

• were in another interventional clinical trial.