The Effect of Type 2 Diabetes and Dietary Regulation on VLDL1-and VLDL2-triglyceride Metabolism
Status:
Completed
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
In this study the investigators wish to compare Very Low-Density Lipoprotein (VLDL) kinetics
in type 2 diabetic males and healthy males postabsorptive and during hyperinsulinemia. The
kinetics is obtained using an ex-vivo VLDL1- and VLDL2-triglyceride labeling technique. The
investigators hypothesis is that the investigators will find an increased VLDL1 production in
type 2 diabetic males, which is not lowered by hyperinsulinemia. Also the investigators wish
to investigate the influence of diet on VLDL1 and VLDL2 production in healthy males, where
the investigators expect less variance in VLDL production when the subject is given an
isocaloric diet.