The Effect of Valproate on Benzodiazepine Withdrawal Severity

• Status: Completed
• Trial end date: 2008-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to determine whether valproate is effective in the treatment of benzodiazepine withdrawal symptoms in subjects receiving maintenance treatment for opiate dependence.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Helsinki University; University of Helsinki
• Treatments: Valproic Acid

Criteria

Inclusion Criteria:

• Diagnosis of benzodiazepine dependence (DSM IV-R)

• Induction of buprenorphine or methadon maintenance treatment, or need of benzodiazepine withdrawal treatment during ongoing buprenorphine/methadon maintenance

Exclusion Criteria:

• Pregnancy

• History of convulsions

• Unstable somatic diseases