The Effect of Vitamin C on GCF Total Oxidant Capacity in Smoker Patients With Periodontitis

• Status: Recruiting
• Trial end date: 2021-12-21
• Target enrollment: 0
• Participant gender: All

Summary

The effect of vitamin C supplementation on GCF total oxidant capacity in smoker patients with periodontitis following non-surgical periodontal therapy.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Treatments: Ascorbic Acid

Criteria

Inclusion Criteria:

• all patients were systemically healthy

• stage III-IV grade B periodontitis

• A minimum of two non-adjacent teeth having sites with ≥ 5 mm interdental clinical attachment loss .

• Radiographic bone loss extending to middle third of root and beyond .

• All patients were heavy smokers i.e ≥ 20 cigarettes / day .

Exclusion Criteria:

• patients who had received any periodontal or antibiotic treatment or vitamins supplementation during the last six months.

• pregnant or lactating women

• patients who refused to provide written informed consent