The Effect of Vitamin D Supplementation on Arterial Stiffness in Diabetic Patients

• Status: Completed
• Trial end date: 2011-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The incidence of type 2 Diabetes Mellitus is increasing at an alarming rate worldwide.

Cardiovascular disease is the leading cause of death in patients with type 2 diabetes.

Recently, increasing amount of evidence suggests that vitamin D may influence various nonskeletal medical conditions, including cardiovascular disease, hypertension, diabetes, cancer, autoimmune disorders and more. The purpose of this trial is to investigate the effect of vitamin D supplementation on 24 hours blood pressure monitoring, arterial stiffness, oxidative stress and inflammation in vitamin D deficient diabetic patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assaf-Harofeh Medical Center
• Treatments: Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Diabetic patients

• Aged 18 years or older

• VITAMIN d deficiency

Exclusion Criteria:

• CCT<30

• A history of treatment with vitamin D supplementation in the last 3 months

• Treatment with nitrates

• Uncontrolled heart failure

• Uncontrolled hypertension and/or any change in the hypertensive medications during the last 1 month.

• Any malignancy with life expectancy of less then 1 year

• Pregnancy