The Effect of Vitamin D Supplementation on HIV-associated Platelet Hyperreactivity
Status:
Completed
Trial end date:
2014-06-01
Target enrollment:
Participant gender:
Summary
Platelets play pivotal role in atherosclerosis and acute cardiovascular events. Platelet
hyperreactivity and increase platelet-monocyte aggregate (PMA) formation are found in HIV
infected patients, which may contribute to the excess cardiovascular risk. Low level of
vitamin D has been associated with the presence of cardiovascular diseases. The aim of our
study is to determine the effect of vitamin D supplementation on platelet activation,
platelet reactivity and platelet-leukocyte complex formation in asymptomatic HIV-infected
patients treated with ART
Phase:
N/A
Details
Lead Sponsor:
Universitas Padjadjaran
Collaborator:
Radboud University
Treatments:
Cholecalciferol Ergocalciferols Vitamin D Vitamins