To investigate the effect of menatetrenone on bone turnover in postmenopausal patients with
osteoporosis. One month of menatetrenone therapy enhanced the secretion and
gamma-carboxylation of osteocalcin. Moderate increases of bone resorption and formation
markers were observed after 6 months. These changes may contribute to fracture prevention in
patients with osteoporosis.
Phase:
Phase 4
Details
Lead Sponsor:
Eisai Limited
Treatments:
Menatetrenone Vitamin K Vitamin K 2 Vitamin MK 7 Vitamins