Overview
The Effect of the Forced Diuresis With Matched Hydration in Reducing Acute Kidney Injury During TAVI
Status:
Completed
Completed
Trial end date:
2019-05-22
2019-05-22
Target enrollment:
0
0
Participant gender:
All
All
Summary
Evaluating whether forced diuresis with matched hydration will reduce the risk of contrast induced nephropathy in patients undergoing Transcatheter Aortic Valve Implantation (TAVI).Phase:
Phase 4Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
Tel-Aviv Sourasky Medical CenterTreatments:
Acetylcysteine
N-monoacetylcystine
Criteria
Inclusion Criteria:1. Subject is 65 years old who is able and willing to give an informed consent.
2. Patients undergoing planned trans-femoral TAVI.
3. Calculated eGFR below 60ml/min/1.73m2 (MDRD)
Exclusion Criteria:
1. History of acute coronary syndrome in the past 30 days.
2. History of congesting heart failure with left ventricular ejection fraction <30% or
exacerbation in the past 30 days.
3. Current dialysis treatment.
4. Known furosemide hypersensitivity.
5. Contraindications to placement of a Foley catheter in the bladder.