The Effect on Anxiolytics With Type of Antiemetic Agents on Postoperative Nausea and Vomiting in High Risk Patients
Status:
Completed
Trial end date:
2020-06-30
Target enrollment:
Participant gender:
Summary
Nausea and vomiting after surgery are one of the complications that occur after general
anesthesia, and the frequency is reported to range from 10% to 80% in the high-risk group.
Several studies have introduced drugs and methods to prevent nausea and vomiting after
surgery. Among them, midazolam administered before surgery is known to have anti-anxiolytic
and sedative effects on the prevention of nausea and vomiting after surgery. It has also been
reported to increase its effectiveness when administered with other antiemetic agents.
The purpose of this study is to compare the effects of administration of combination with
midazolam and different antiemetic agents on the prevention of postoperative nausea and
vomiting in high-risk patients.