The Effectiveness Of Intravenous TXA on Reducing Perioperative Blood Loss For Patients Undergoing PAO
Status:
Withdrawn
Trial end date:
2019-07-23
Target enrollment:
Participant gender:
Summary
In this research study the investigators want to learn more about how a medication called
tranexamic acid (TXA) could help reduce bleeding during Periacetabular Osteotomy (PAO)
surgery. TXA is approved by the Food and Drug Administration (FDA) for the reduction of
bleeding for many types of surgical procedures. TXA works by slowing the breakdown of blood
clots and helps to prevent bleeding. From previous studies, TXA has been shown to effectively
prevent bleeding in patients undergoing heart, spine and skull remodeling surgeries.
As PAO surgery has been associated with significant blood loss when compared to other types
of joint surgeries. In order to try and avoid bleeding that may lead to complications,
different strategies can be used. In this research study the investigators want to learn more
about how a medication called tranexamic acid (TXA) could help reduce bleeding during PAO
surgery.
Phase:
Phase 4
Details
Lead Sponsor:
Boston Children's Hospital Boston Children’s Hospital