The Effectiveness of Gabapentin for Post-operative Pain Following Cesarean Section
Status:
Completed
Trial end date:
2011-02-01
Target enrollment:
Participant gender:
Summary
Gabapentin has been very effective at treating pain after knee and hip operations,
hysterectomies, and many other types of operations. A previous study at the investigators'
hospital found that a single pre-operative dose of 600mg gabapentin produced a significant
reduction in pain after caesarean section. However, 19% complained of sedation. The purpose
of this study is to see whether a reduced dose of gabapentin will produce a similar
improvement in pain scores while avoiding adverse effects such as sedation or dizziness. The
objective of this study is to compare the efficacy of a single pre-operative oral dose of
gabapentin 300mg, versus 600mg and placebo in women undergoing Cesarean section. The
investigators' hypothesis is that gabapentin 300mg will result in decreased pain scores
similar to gabapentin 600mg, but with reduced side effects.
Phase:
N/A
Details
Lead Sponsor:
Samuel Lunenfeld Research Institute, Mount Sinai Hospital