The Effectiveness of Metoprolol in the Prevention of Syncope Recurrence in Children and Adolescents

• Status: Completed
• Trial end date: 2003-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study to evaluate the effectiveness of metoprolol versus conventional treatment in the prevention of syncope recurrence in children and adolescents.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Peking University First Hospital
• Treatments: Metoprolol

Criteria

Inclusion Criteria:

• Children with a history of syncope were included if they had had at least three syncopal episodes per year and had a positive head-up tilt test result.

Exclusion Criteria:

• Patients were excluded if they had:

• Other causes of syncope;

• Cardiovascular and/or systemic disease;

• Systolic blood pressure >130 mm Hg or diastolic blood pressure >90 mm Hg； or

• History of asthma, impaired liver function, Ⅱ to Ⅲ degrees of atrioventricular block, sinus bradycardia < 40 beats/min, or other contraindications for β-blockers.