The Effects of Anaesthesia on Cerebral Oxygenation and Cognitive Function in Carotid Endarterectomy

• Status: Completed
• Trial end date: 2016-06-01
• Target enrollment: 0
• Participant gender: Male

Summary

Volatile anesthetics interfere with cerebral blood flow and reperfusion-ischemia injury via the mechanism known as a preconditioning. A transient deterioration of local hemodynamics and oxygenation during carotid endarterectomy (CEE) might involve both hemispheres of brain and affect postoperative cognitive function. The goal of this study was to assess the effects of anesthetics on perioperative cerebral oxygenation and cognitive functions.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Northern State Medical University
• Treatments: Anesthetics; Propofol; Sevoflurane

Criteria

Inclusion Criteria:

• > 18 years

• Male gender

• Informed consent

• Symptomatic carotid stenosis > 75%

Exclusion Criteria:

• Contralateral carotid occlusion

• Known allergy to the one of the compared medications