The Effects of Butyrate Enemas on Visceral Perception

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

During this double blind, placebo controlled, randomised cross over study, healthy volunteers received an enema once daily for one week containing either placebo (saline), 50mM butyrate or 100mM of butyrate. Before and directly after each test period a barostat protocol was performed to measure parameters for visceral perception.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Maastricht University; Maastricht University Medical Center
• Treatments: Butyric Acid

Criteria

Inclusion Criteria:

• healthy

Exclusion Criteria:

• age, under 18 or over 65

• use of pre- or probiotics during study and 3 months previous to study

• previous bowel complaints

• gastrointestinal disease or abdominal surgery