The Effects of Cannabidiol (CBD) on Electrical and Autonomic Cardiac Function in Children With Severe Epilepsy
Status:
Terminated
Trial end date:
2018-12-01
Target enrollment:
Participant gender:
Summary
The investigators propose to study the effects of cannabidiol (CBD) on cardiac electrical
function and the autonomic nervous system in children with Dravet syndrome (DS) and
Lennox-Gastaut syndrome (LGS), when the CBD is administered as an artisanal oil obtained
through state dispensaries or other sources. The intent is to begin to assess potential risks
and benefits of this therapy in a vulnerable patient population by characterizing the effects
of CBD on EKG findings, heart rate variability and the occurrence of seizures.