The Effects of Chlorhexidine/Thymol Varnish on Partial Denture Patient

• Status: Withdrawn
• Trial end date: 2020-12-10
• Target enrollment: 0
• Participant gender: All

Summary

Cervitec, a chlorhexidine based varnished has been proven to reduce caries risk in younger populations. This study wants to investigate if the use of this product would reduce the risk of losing abutment teeth on patients that are wearing partial dentures as the literature has proven that these teeth are more prone to caries and periodontal disease.

The primary objectives of this research project are to:

1. Assess if the topical application of CHX/thymol varnish every three months on partial denture abutment teeth results in a clinicallu significant decrease in any loss of attachment compared to no application, and

2. Assess if the topical application of CHX/thymol vanirhs every three months on partial denture abutment teeth results in a clinically significant decrease in carious lesion development or progression compared to no application.

The secondary objectives of this research project are to:

1. Assess of the topical application of CHX/thymol varnish every three months on partial denture abutment teeth compared to no application results in a clinically significant difference in:

1. Bleeding on probing (BoP).

2. Plaque formation.

3. Periodontal pocket depths.

4. Microbial composition and GCF cytokine profile of the sub gingival environment.

5. The patients self perception of oral health.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Rosa Moreno Lopez
• Collaborator: Ivoclar Vivadent AG
• Treatments: Chlorhexidine; Chlorhexidine gluconate; Thymol

Criteria

Inclusion Criteria:

• Patients that are going to have a new denture fitted at the Dental School of the University of Aberdeen and Penninsula Dental School.

• Patients aged 18 years or over.

Exclusion Criteria:

• Patients that already have a denture.

• Patients that are taking antibiotics.

• Patients allergic to any of the components of the products.

• Pregnant women.

• Severe systemic illness.

• Patient with active periodontal disease (BoP and pockets ≥3mm) on abutment teeth.

• Presence of caries on abutment teeth.