The Effects of Chlorhexidine/Thymol Varnish on Partial Denture Patient
Status:
Withdrawn
Trial end date:
2020-12-10
Target enrollment:
Participant gender:
Summary
Cervitec, a chlorhexidine based varnished has been proven to reduce caries risk in younger
populations. This study wants to investigate if the use of this product would reduce the risk
of losing abutment teeth on patients that are wearing partial dentures as the literature has
proven that these teeth are more prone to caries and periodontal disease.
The primary objectives of this research project are to:
1. Assess if the topical application of CHX/thymol varnish every three months on partial
denture abutment teeth results in a clinicallu significant decrease in any loss of
attachment compared to no application, and
2. Assess if the topical application of CHX/thymol vanirhs every three months on partial
denture abutment teeth results in a clinically significant decrease in carious lesion
development or progression compared to no application.
The secondary objectives of this research project are to:
1. Assess of the topical application of CHX/thymol varnish every three months on partial
denture abutment teeth compared to no application results in a clinically significant
difference in:
1. Bleeding on probing (BoP).
2. Plaque formation.
3. Periodontal pocket depths.
4. Microbial composition and GCF cytokine profile of the sub gingival environment.
5. The patients self perception of oral health.