The Effects of Craving and Abstinence From Cigarettes on Brain Metabolism in Smokers
Status:
Completed
Trial end date:
2007-10-01
Target enrollment:
Participant gender:
Summary
Craving and withdrawal from smoking cigarettes are major factors for relapse. We investigated
craving for cigarettes in smokers undergoing pharmacological treatment with Bupropion
(Zyban). We compare cue-induced reactivity to smoking videos in smokers who were successfully
treated with Bupropion to smokers who are still smoking. We measured the brain's metabolic
activity in response to smoking and neutral cues in Positron Emission Tomography using FDG.