The Effects of Dexmedetomidine on Postoperative Renal Function in Valvular Heart Surgery

• Status: Unknown status
• Trial end date: 2015-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of study is to compare the incidence of acute kidney injury in patients receiving perioperative dexmedetomidine or placebo undergoing valvular heart surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yonsei University
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

• adult patients over the age of 20 scheduled for valvular heart surgery

Exclusion Criteria:

• Left ventricular-ejection fraction < 30%

• Preexisting congestive heart failure

• Severe coronary artery disease

• Hemodynamically unstable arrhythmia

• Cardiogenic shock during perioperative period

• Ventricular assist device

• Severe renal dysfunction (eGFR < 15ml/min per 1.73m2)