The Effects of Increased Central Serotonergic Activity on Information Processing

• Status: Completed
• Trial end date: 2006-03-01
• Target enrollment: 0
• Participant gender: Male

Summary

It is of great clinical relevance to know if selective serotonin re-uptake inhibitors affect information processing. Our hypothesis was that aspects of information processing would be disturbed whereas others would improve.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Copenhagen
• Collaborators: Glostrup University Hospital, Copenhagen; Lundbeck Foundation
• Treatments: Citalopram; Dexetimide

Criteria

Inclusion Criteria:

• Male subjects

• Good Physical and Mental Health meeting criteria "never mentally ill", which will be evaluated with a medical history checklist, ECG

• Non smokers

Exclusion Criteria:

• Current use of any medication

• Any subject who has received any investigational medication within 30 days prior to the start of this study

• History of neurologic illness

• History of psychiatric illness in first-degree relatives, evaluated with DSM-IV criteria

• History of alcohol and drug abuse. Positive urine screening for amphetamine, cocaine, cannabis, or esctacy.