The Effects of Insulin Detemir and Gliclazide-MR Treatments on Endothelial Functions in Patients With Type 2 Diabetes
Status:
Completed
Trial end date:
2012-06-01
Target enrollment:
Participant gender:
Summary
The main purpose of this study is to analyze the effects of the addition of sulfonylurea
(gliclazide MR) or ,alternatively, basal insulin (insulin detemir) to life-style modification
and metformin treatment as a second step treatment in type 2 diabetes mellitus on endothelial
cell functions. The second goal is to identify the effects of these treatment alternatives on
body-mass index, the changes in body fat mass, insulin resistance and on the insulin
secretion capacity of beta cells. The third aim of this study is to determine the success
rates of these treatment alternatives on glycemic control at 6 months follow-up.
Phase:
N/A
Details
Lead Sponsor:
Ankara University
Collaborators:
Hacettepe University The Scientific and Technological Research Council of Turkey Tubitak