The Effects of L-arabinose on Intestinal Sucrase Activity in Man

• Status: Completed
• Trial end date: 2006-01-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of this study is to investigate the effect of L-arabinose in a sugar-rich meal on intestinal sucrase activity in healthy volunteers by measuring postprandial blood glucose and insulin, and selected intestinal hormonal responses to increasing doses of L-arabinose.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Copenhagen
• Collaborator: Danisco

Criteria

Inclusion Criteria:

• healthy males

• BMI between 18.4-25 kg/m2

• age between 18 and 30

Exclusion Criteria:

• donation of blood 3 months before or during the study

• gastrointestinal disorders, diabetes, hypertension, hyperlipidemia, chronic infectious disease (HIV or hepatitis)

• smoking

• consumption of more than 21 alcoholic drinks/week

• elite athletes

• on medication