The Effects of Laxative-probiotic Sequential Treatment in the Irritable Bowel Syndrome Patients

• Status: Completed
• Trial end date: 2016-07-01
• Target enrollment: 0
• Participant gender: All

Summary

the laxative-probiotic sequential treatment might reduce the symptoms of IBS and alter the fecal microbiota of the patients in a more robust manner .

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shandong University
• Treatments: Cathartics; Laxatives

Criteria

Inclusion Criteria:

• the presence of Rome III criteria for IBS ;

• Patients scheduled for colonoscopy examination or having negative screening examinations

• Aged between 18 and 65 years old

Exclusion Criteria:

• Antibiotic, probiotic or laxative usage within 4 weeks.

• organic gastrointestinal diseases

• Severe systematic disease: diabetes mellitus, hepatic, renal or cardiac dysfunction, thyroid disease or tumor etc.

• pregnancy or lactation.

• previous major or complicated abdominal surgery.

• severe endometriosis and dementia