The Effects of Long Term Inhalation of Hypertonic Saline in Subjects With Cystic Fibrosis
Status:
Completed
Trial end date:
2003-11-01
Target enrollment:
Participant gender:
Summary
The effect of long term inhalation of hypertonic saline in subjects with cystic fibrosis on
lung function, incidence of respiratory tract infections, quality of life, quantitative
microbiology and sputum cytokine profile. The hypothesis is that regular inhalation of
nebulised hypertonic saline will have a beneficial effect on lung function and other clinical
outcomes with no adverse effects on infection and inflammation in adults and children with
cystic fibrosis.
Phase:
Phase 3
Details
Lead Sponsor:
Royal Prince Alfred Hospital, Sydney, Australia
Collaborators:
Cystic Fibrosis Foundation Cystic Fibrosis Foundation Therapeutics Cystic Fibrosis Trust National Health and Medical Research Council, Australia