The Effects of Metformin on Glycemic Control and Insulin Sensitivity in Adolescents With T1DM
Status:
Completed
Trial end date:
2018-01-01
Target enrollment:
Participant gender:
Summary
The investigators intends to carry out a randomized, cross-over, prospective study which will
last 48 weeks in youth with T1DM followed up by the center. The purpose is to observe the
effects of metformin on glycemic control and insulin sensitivity in adolescents with T1DM
based on insulin therapy by using 72h CGMS and hyperinsulinemic euglycemic clamps.