The Effects of Multi-strain Probiotics in Adults With Diarrhea Predominant Irritable Bowel Syndrome

• Status: Unknown status
• Trial end date: 2013-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators will evaluate the efficacy of multi-strain probiotics in adults with diarrhea predominant irritable bowel syndrome.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Seoul National University Hospital

Criteria

Inclusion Criteria:

• willing to consent/undergo necessary procedures

• between the age of 19 and 75 years

• diarrhea predominant irritable bowel syndrome (satisfied with Rome II criteria)

Exclusion Criteria:

• uncontrolled hypertension (Blood pressure > 180/110 mmHg)

• uncontrolled diabetes mellitus (FBS > 200 mg/dL)

• malignancy, cerebrovascular disease, cardiovascular disease

• history of abdominal surgery except appendectomy and hernia repair

• inflammatory bowel disease

• clinically or laboratory-confirmed gastroenteritis

• the use of motility drug or dietary fiber supplement in 2 weeks

• serum Cr > 2 x Upper normal limit

• AST or ALT > 2 x Upper normal limit

• Pregnancy, Lactating woman