The Effects of Nasal Airflow on Upper Airway Dilator Muscles During Sleep
Status:
Unknown status
Trial end date:
2018-05-12
Target enrollment:
Participant gender:
Summary
Obstructive sleep apnea (OSA) is an increasingly prevalent disorder characterized by repeated
upper airway collapse during sleep, resulting in oxygen desaturation and frequent arousals.
The etiology of OSA remains unclear.
Many studies indicates an association between nasal obstruction and apnea. However,the
precise nature of this relationship is far from clear and the importance of resistance to
nasal airflow in the pathogenesis of airway collapse in OSA patients remains contentious.
In this study, investigators perform 4 different ways to change subjective or objective
patency of nasal cavity and observe the effects of the nasal airflow on nocturnal breathing,
sleep,and upper airway muscles in OSA patients.