The Effects of Preoperative Scopolamine Patch Application on the Postoperative Nausea and Vomiting in MVD Surgery

• Status: Unknown status
• Trial end date: 2017-10-01
• Target enrollment: 0
• Participant gender: All

Summary

A Single-center, randomized, prospective, experimental, double-blind comparison study for effects of preoperative scopolamine patch application on the postoperative nausea and vomiting in microvascular decompression surgery

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Hospital
• Treatments: Butylscopolammonium Bromide; Scopolamine; Scopolamine Hydrobromide

Criteria

Inclusion Criteria:

1. Those of either hemi-facial spasm or trigeminal neuralgia, who undergo microvascular decompression (MVD), understand study objectives and voluntarily consent with participation.

2. Adequate communication ability enough to understand and answer the questionnaire.

3. Age ≥ 18 years, and ≤ 65 years.

4. ASA Physical Status Classification from 1 to 2. Class 1: A normal healthy patient Class 2: A patient with mild systemic disease

5. Those who is discharged to general ward, not intensive care unit (ICU) after operation

6. Normal liver or kidney function

Exclusion Criteria:

1. More than one craniotomy in the same period of admission

2. Pregnant or lactating women

3. Narrow-angle glaucoma

4. Pyloric stenosis, intestinal obstruction, bladder obstruction

5. Bradycardia

6. Voiding difficulty such as benign prostate hypertrophy (BPH)

7. Any history of hypersensitivity to ointment base or scopolamine patch