Overview

The Effects of Quetiapine (Seroquel XR) on Sleep During Alcohol Abstinence

Status:
Completed

Trial end date:
2009-12-01

Target enrollment:
0

Participant gender:
All

Summary

The primary purpose of this study is to determine how efficacy of quetiapine (seroquel XR) in improving the sleep in recovering alcohol dependent subjects.

Phase:

Phase 3

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Subhajit Chakravorty

Treatments:

Quetiapine Fumarate

Criteria

Inclusion Criteria: subjects between the ages of 18-65 years, with a DSM-IV diagnosis of
current alcohol dependence (past year), can speak, understand, and print in English, and is
capable of giving written informed consent

Exclusion Criteria: Positive urine drug screen for opioids, cocaine, or amphetamine
(excluding THC), dependence on other drugs excluding alcohol/nicotine/cannabis over the
past year, unstable psychiatric, medical disorders, cataracts [posterior capsular/ nuclear
(grade NS3 or more), currently on any maintenance psychotropic medications affecting sleep,
currently pregnant, nursing, or not using a reliable method of contraception; history of
hypersensitivity to antipsychotic drugs, including quetiapine, severe cognitive impairment,
severe untreated obstructive sleep apnea, and inadequately controlled diabetes mellitus.