The Effects of Remifentanil and Remifentanil-Alfentanil Administration in Children
Status:
Completed
Trial end date:
2014-01-01
Target enrollment:
Participant gender:
Summary
Sevoflurane is widely and frequently used in pediatric anesthesia due to its non-irritating
airway properties, rapid induction and emergence. However, it is associated with emergence
agitation (EA) in children. EA may cause injury to the child or to the surgical site and is a
cause of stress to both caregivers and families. Various pharmacologic agents have been
suggested to reduce EA. But the effect of remifentanil on EA is still controversial. This
study was designed to compare the effects of remifentanil and remifentanil combining
alfentanil on EA in children undergoing ophthalmic surgery with sevoflurane anesthesia.