Overview

The Effects of Remifentanil and Remifentanil-Alfentanil Administration in Children

Status:
Completed

Trial end date:
2014-01-01

Target enrollment:
0

Participant gender:
All

Summary

Sevoflurane is widely and frequently used in pediatric anesthesia due to its non-irritating airway properties, rapid induction and emergence. However, it is associated with emergence agitation (EA) in children. EA may cause injury to the child or to the surgical site and is a cause of stress to both caregivers and families. Various pharmacologic agents have been suggested to reduce EA. But the effect of remifentanil on EA is still controversial. This study was designed to compare the effects of remifentanil and remifentanil combining alfentanil on EA in children undergoing ophthalmic surgery with sevoflurane anesthesia.

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Hallym University Medical Center

Treatments:

Alfentanil
Anesthetics
Remifentanil
Rocuronium
Sevoflurane
Thiopental

Criteria

Inclusion Criteria:

- children who were scheduled to undergo ophthalmic surgery under general anesthesia

Exclusion Criteria:

- developmental delay, neurologic or psychologic disease,

- history of sleep apnea,

- or history of general anesthesia