Overview The Effects of Sedatives on Tobacco Use Disorder Status: Recruiting Trial end date: 2022-02-01 Target enrollment: Participant gender: Summary This proposal will obtain preliminary data on the effect of a single sub-anesthetic dose of a sedative on cigarette craving and smoking behavior as well as measuring tolerability and acceptability. Phase: Phase 1/Phase 2 Details Lead Sponsor: University of ArkansasTreatments: Hypnotics and SedativesKetamineMidazolam