The Effects of Sevelamer Carbonate on Diabetic Nephropathy
Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to see if taking a medication can lower the amount of oxidants
from food that go into our body. Previous research shows that if the investigators lower the
oxidants from food in people with diabetes, this simple change lowers different risks for
heart disease and the worsening of kidney disease. The investigators focus on a specific type
of oxidant, advanced glycation endproducts (AGEs). A previous, smaller study, conducted by
our group showed that a drug, already approved by the FDA, will lower AGEs in the
investigators compared Renvela® to Tums®. Both of these drugs have few side effects and have
been used for a long time in patients with diabetes and kidney disease. While our previous
study was interesting, it was just too small to be able to be sure that it will help all
people with diabetes, or if the good effects the investigators found were simply due to
chance. The investigators are doing this new study to confirm or deny the possibility that
Renvela® can really help people with diabetes and kidney disease.