The Effects of Tranexamic Acid on Joint Inflammation and Cartilage Health in Anterior Cruciate Ligament Injured Patients
Status:
Recruiting
Trial end date:
2022-12-31
Target enrollment:
Participant gender:
Summary
Patients who tear their ACL are at high risk for developing arthritis (post-traumatic
osteoarthritis-PTOA) just 10 years later. Joint bleeding and inflammation contribute to
deterioration of joint health. This study will determine whether treatment with Tranexamic
Acid (TXA), an FDA approved medication that reduces bleeding right after ACL injury and
reconstructive surgery reduces inflammation and improves joint health as a new strategy to
prevent or delay the onset of PTOA.