The Efficacy and Safety of Different Concentrations of Localized Injections of Steroids in the Treatment of Alopecia Areata

• Status: Completed
• Trial end date: 2014-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Alopecia areata (AA) is a disease characterized by areas of hair loss. Localized steroid injections is the standard treatment for limited disease. There are no existing studies that compare different concentrations of steroids in the treatment of AA. This study will compare the efficacy and safety of different concentrations of localized steroid injections in the treatment of AA. Six treatment sessions will be done over 6 to 9 months. The investigators will compare the following concentrations: 2,5mg/ml, 5mg/ml, 10mg/ml, and normal saline.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of British Columbia
• Treatments: Triamcinolone; Triamcinolone Acetonide; Triamcinolone diacetate; Triamcinolone hexacetonide

Criteria

Inclusion Criteria:

• Age > 18 years

• Less than 50% scalp involvement

• Patients should have a patch of at least 4.5 cm in the smallest diameter

Exclusion Criteria:

• Current episode of alopecia areata for longer than 2 years

• Evidence of hair regrowth at baseline

• Patients who received treatment with a topical, intralesional, or systemic agent within the past month

• Rapidly progressing disease

• Hypersensitivity to Triamcinolone acetonide or vehicle

• Pregnancy or breast-feeding