The Efficacy and Safety of Montelukast Sodium in the Prevention of Bronchopulmonary Dysplasia
Status:
Completed
Trial end date:
2013-10-01
Target enrollment:
Participant gender:
Summary
This study is multicentered, prospective, randomized, opened, parallel, intervention study.
The aim of this study is to evaluate the efficacy and safety of Montelukast sodium in the
prevention of bronchopulmonary dysplasia (BPD) in preterm infant, below 32weeks gestational
age.
The investigators evaluate the first effectiveness through the morbidity and mortality of
bronchopulmonary dysplasia. And then, the investigators evaluate the second effectiveness
through the oxygen index, the usage of mechanical ventilator about taking medicine after 2
Weeks, Oxygen Utilization After 4 Weeks, Proinflammatory Cytokine through the bronchial
lavage fluid.
Phase:
Phase 2
Details
Lead Sponsor:
Ajou University School of Medicine
Collaborators:
Gangnam Severance Hospital Korea University Seoul National University Hospital Severance Hospital