The Efficacy and Safety of Tropisetron in Preventing Emergence Delirium

• Status: Recruiting
• Trial end date: 2022-03-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the efficacy and safety of Tropisetron in preventing emergence delirium.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Beijing Chao Yang Hospital
• Treatments: Tropisetron

Criteria

Inclusion Criteria:

1. Written consent given

2. Scheduled to undergo elective non-cardiac surgeries under general anesthesia

3. ASA Physical Score I-III

Exclusion Criteria:

1. Patients with a history of neurological disease, such as Alzheimer disease.

2. Patients with a history of psychiatric disease

3. Patients with a medication history of antipsychotic drugs over the last 30 days prior to enrollment.

4. Unable to complete neuropsychological testing including patients with severe visual or hearing impairment.

5. the Montreal Cognitive Assessment (MoCA) scores below 10

6. Patients who have severe intraoperative adverse events, such as cardiac arrest.

7. Patients with contraindication of tropisetron.