The Efficacy of Botulinum Toxin vs. Corticosteroid for the Treatment of Refractory Plantar Fasciitis

• Status: Recruiting
• Trial end date: 2022-05-01
• Target enrollment: 0
• Participant gender: All

Summary

This single-blinded, randomized-controlled trial compares the efficacy of ultrasound-guided onabotulinumtoxinA (BTX-A) injections to the flexor digitorum brevis with current standard of care corticosteroid injections to the plantar fascia for the treatment of refractory plantar fasciitis in patients that have failed six weeks of non-operative treatment.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Western Institute for Veterans Research
• Treatments: abobotulinumtoxinA; Botulinum Toxins; Botulinum Toxins, Type A; Cortisone; Dexamethasone

Criteria

Inclusion Criteria:

1. Diagnosed increased pain when pressure applied at the medial calcaneal tubercle

2. X-ray negative for calcaneal fractures, tumors, enthesopathy or osteoarthritis

3. Patient with plantar fasciitis who have failed 6 weeks of non-operative treatment

Exclusion Criteria:

1. Prior botulinum toxin injections in the plantar fascia

2. Any botulinum toxin injections in the past 3 months

3. Cortisone injection in the plantar fascia in the previous 3 months

4. Previous surgery on the plantar fascia

5. Active workers compensation claim for plantar fasciitis

6. Active infection or fever

7. Botox or steroid allergy

8. Pregnancy